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Research programme 04
Diagnostics and therapeutic translation
We develop isoform-specific tools and apply them to cancer predisposition, biomarker development and therapeutic strategies.
This programme develops the enabling technologies for isoform-resolved p53 biology, including antibodies, experimental protocols and defined models.
Translational directions include broader cancer genetics, liquid-biopsy concepts and strategies that use p53-isoform biology to improve engineered antitumour T cells.
